Anti-BAF53a Antibody

Our Anti-BAF53a mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N336B/83. It detects human, mouse, and rat BAF53a, and is purified by Protein A chromatography. It is great for use in ICC, WB.

Product Specifications

Background

Actin-like protein 6A, or BAF Complex 53 KDa Subunit (BAF53a) is encoded by the gene ACTL6A and is a member of actin-related proteins family. It is a subunit of the neuron specific chromatin remodeling complex (nBAF complex) . BAF53a is thought to be involved in transcriptional activation and repression of chromatin remodeling. BAF53a is a subunit of the neural progenitors-specific chromatin remodeling complex (npBAF complex) . BAF53a is expressed in many different cell types. Diseases associated with ACTL6A include Coffin-siris syndrome and Brachymorphism-Onychodysplasia-Dysphalangism Syndrome.

Short Description

Our Anti-BAF53a mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N336B/83. It detects human, mouse, and rat BAF53a, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, ELISA.

Synonyms

Actin-like protein 6A (53 kDa BRG1-associated factor A) (Actin-related protein Baf53a) (ArpNbeta) (BRG1-associated factor 53A) (BAF53A) (INO80 complex subunit K)

Gene Name

ACTL6A BAF53 BAF53A INO80K

UniProt

O96019

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 43-119 (MVVERDDGSTLMEIDGDKGKQGGPTYYIDTNALRVPRENMEAISPLKNGMVEDWDSFQAILDHTYKMHVKSEASLHP, actin subdomain 2) of human BAF53a (accession number O96019) produced recombinantly in E. Coli

Target

BAF53a

Clonality

Monoclonal

Isotype

IgG2b

Clone

N336B/83

Type

Primary Antibody

Applications

WB, IHC, ICC, ELISA

Field of Research

Neurogenesis and Development/Transcription Regulation

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Molecular Weight

53 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.