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Anti-NrCAM Antibody

Our Anti-NrCAM mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N343/26. It detects mouse and rat NrCAM, and is purified by Protein A chromatography. It is great for use in ICC, WB.

Product Specifications

Background

Neuronal Cell Adhesion Molecule is encoded by the gene NRCAM. NRCAM is a member of the immunoglobulin superfamily, L1/neurofascin/NgCAM family. NRCAM is an ankyrin-binding protein that is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. NRCAM also may play a role in cell-cell communication via signalling from its intracellular domain to the actin cytoskeleton during directional cell migration. NRCAM is expressed in the brain. Diseases associated with NRCAM include Masa Syndrome and Autism.

Short Description

Our Anti-NrCAM mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N343/26. It detects mouse and rat NrCAM, and is purified by protein a chromatography. It is great for use in WB, ICC, ELISA.

Synonyms

Neuronal cell adhesion molecule (Nr-CAM) (Neuronal surface protein Bravo) (mBravo) (NgCAM-related cell adhesion molecule) (Ng-CAM-related)

Gene Name

Nrcam Kiaa0343

UniProt

Q810U4

Host

Mouse

Reactivity

Mouse and Rat

Immunogen

Fusion protein amino acids 30-845 (extracellular domain) of mouse NrCAM (accession number Q810U4) produced recombinantly in E. Coli

Target

NrCAM

Clonality

Monoclonal

Isotype

IgG2a

Clone

N343/26

Type

Primary Antibody

Applications

WB, ICC, ELISA

Field of Research

Cell Adhesion Molecules

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Molecular Weight

160 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Mouse

ICC Quality Control

1

Conjugate

Unconjugated

RRID

AB_2315900

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