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Anti-Kv1.4 Potassium Channel (Extracellular) Antibody FL650 Conjugate

Selected Variant

75-316-FL650

Size: 200 µL

Our Anti-Kv1.4 potassium channel (extracellular) mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L71/5. It detects mouse and rat Kv1.4 potassium channel (extracellular), and is purified by Protein A chromatography. It is great for use in ICC.

Product Specifications

Background

Potassium voltage-gated channel subfamily A member 4 or Kv1.4 is encoded by the gene KCNA4. Kv1.4 is a potassium channel subunit is a member of the potassium channel, voltage-gated, shaker-related subfamily. Potassium channels form homotetrameric and heterotetrameric channels in the membrane with various other related proteins, including KCNA2, KCNA4, KCNA5, KCNA6, KCNA7. Kv1.4 is expressed in brain, and at lower levels in the testis, lung, kidney, colon, heart and adrenal tissue. In brain, Kv1.4 is located in the soma, dendrite and axon terminus of neurones in most regions of the brain.

Short Description

Our Anti-Kv1.4 potassium channel (extracellular) mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L71/5. It detects mouse and rat Kv1.4 potassium channel (extracellular), and is purified by protein a chromatography. It is great for use in ICC.

Synonyms

Potassium voltage-gated channel subfamily A member 4 (RCK4) (RHK1) (RK3) (Voltage-gated potassium channel subunit Kv1.4)

Gene Name

Kcna4

UniProt

P15385

Host

Mouse

Reactivity

Mouse and Rat

Immunogen

Fusion protein amino acids 336-370 (DDRDLIMALSAGGHSRLLNDTSAPHLENSGHTIFN, extracellular S1-S2 linker) of rat Kv1.4 (accession number P15385) produced recombinantly in E. Coli

Target

Kv1.4 potassium channel (extracellular)

Clonality

Monoclonal

Isotype

IgG1

Clone

L71/5

Type

Primary Antibody

Applications

ICC

Field of Research

Ion Channels and Modulators/K+ Channels

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

98 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Rat

ICC Quality Control

1

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

RRID

AB_2940107

Price

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