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Anti-THAP1 Antibody FL490 Conjugate

Our Anti-THAP1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N325B/65. It detects human THAP1, and is purified by Protein A chromatography. It is great for use in ICC.

Product Specifications

Background

THAP (Thanatos-associated protein) domain-containing, apoptosis-associated protein 1) domain-containing protein 1, Nuclear Proapoptotic Factor or Dystonia 6, Torsion (Autosomal Dominant) is encoded by the gene THAP1. THAP1 is a DNA-binding transcription regulator involved in endothelial cell proliferation, G1/S cell-cycle progression and is thought to play a role in apoptosis. Thap1 is expressed in many tissues including heart, skeletal muscle, kidney, liver, brain and placenta. Diseases associated with this gene include Dystonia.

Short Description

Our Anti-THAP1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N325B/65. It detects human THAP1, and is purified by protein a chromatography. It is great for use in ICC.

Synonyms

THAP domain-containing protein 1

Gene Name

THAP1

UniProt

Q9NVV9

Host

Mouse

Reactivity

Human

Immunogen

Fusion protein amino acids 1-213 (full-length) of human THAP1 (accession number Q9NVV9) produced recombinantly in E. Coli

Target

THAP1

Clonality

Monoclonal

Isotype

IgG3

Clone

N325B/65

Type

Primary Antibody

Applications

ICC

Field of Research

Rare Diseases

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

30 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

ICC Quality Control

1

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

RRID

AB_2940080

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