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Anti-Arl13b Antibody

Our Anti-Arl13b mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N295B/66. It is KO validated, detects human, mouse, non-human primate, rat, and zebrafish Arl13b, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Product Specifications

Background

ADP-ribosylation factor-like protein 13B (ARL13B), also known as ADP-ribosylation factor-like protein 2-like 1. Arl13B is a small GTPase with both N-terminal and C-terminal guanine nucleotide-binding motifs. Arl13B is localized to the membrane of cilia and expressed in Neuroepithelial cells and developing radial glia of the developing cerebral cortex. Mutations in this gene are the cause of Joubert syndrome 8.

Short Description

Our Anti-Arl13b mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N295B/66. It is KO validated, detects human, mouse, non-human primate, rat, and zebrafish Arl13b, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, ELISA.

Synonyms

ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1) (Protein hennin)

Gene Name

Arl13b Arl2l1

UniProt

Q640N2

Host

Mouse

Reactivity

Human, Mouse, Non-Human Primate, Rat, and Zebrafish

Immunogen

Fusion protein amino acids 208-427 (C-terminus) of mouse Arl13b (accession number Q640N2) produced recombinantly in E. Coli

Target

Arl13b

Clonality

Monoclonal

Isotype

IgG2a

Clone

N295B/66

Type

Primary Antibody

Applications

WB, IHC, ICC, ELISA

Field of Research

Rare Diseases

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Molecular Weight

50 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

IHC Dilution

1:500

WB Dilution

1:1000

Specificity

Does not cross-react with Arl13a (based on KO validation results)

ICC Dilution

1:500

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Mouse

WB Brain Quality Control

1

Conjugate

Unconjugated

RRID

AB_11001586

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