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Anti-Rem2 Antibody FL650 Conjugate

Our Anti-Rem2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N324/2. It detects mouse and rat Rem2, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

Rad And Gem-Like GTP-Binding Protein 2 or GTP-binding protein REM 2 is encoded by the gene Rem2 and is a member of the small GTPase superfamily and the Rad/Rem/Rem2/Gem/Kir (RGK) subfamily. REM2 binds GTP and plays roles in diverse processes including modulation of calcium channel currents, (Ref Zheng JQ et al. 2007), mediation of excitatory and inhibitory synapse development (Ref: Paradis et al. 2007) . REM2 is expressed in brain and kidney. Diseases associated with this gene include Long Qt Syndrome.

Short Description

Our Anti-Rem2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N324/2. It detects mouse and rat Rem2, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

GTP-binding protein REM 2 (Rad and Gem-like GTP-binding protein 2)

Gene Name

Rem2

UniProt

Q9WTY2

Host

Mouse

Reactivity

Mouse and Rat

Immunogen

Fusion protein amino acids 1-341 (full-length) of rat Rem2 (accession number Q9WTY2)

Target

Rem2

Clonality

Monoclonal

Isotype

IgG1

Clone

N324/2

Type

Primary Antibody

Applications

IHC, ICC

Field of Research

Cell Signaling/G Protein Signaling

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

45 kDa (and larger due to oligomerization)

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

Does not cross-react with Rad, Gem or Rem1

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Rat

WB Brain Quality Control

1

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

RRID

AB_2940023

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