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Anti-Brevican Antibody FL650 Conjugate

Our Anti-Brevican mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N294A/6. It is KO validated, detects mouse and rat Brevican, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

Brevican core protein, Chondroitin sulfate proteoglycan 7 or Brain-enriched hyaluronan-binding protein is encoded by the gene BCAN and is a member of the lectican family of chondroitin sulfate proteoglycans. Brevican is involved in the development and formation of the brain extracellular matrix and may be involved in malignancy of brain tumor cells. Brevican is developmentally regulated and specifically expressed in the central nervous system. Diseases associated with this gene include Low-Grade Astrocytoma.

Short Description

Our Anti-Brevican mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N294A/6. It is KO validated, detects mouse and rat Brevican, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

Brevican core protein (Brain-enriched hyaluronan-binding protein) (BEHAB)

Gene Name

Bcan Behab

UniProt

P55068

Host

Mouse

Reactivity

Mouse and Rat

Immunogen

Fusion protein amino acids 219-655 of rat Brevican (accession number P55068) produced recombinantly in E. Coli

Target

Brevican

Clonality

Monoclonal

Isotype

IgG2b

Clone

N294A/6

Type

Primary Antibody

Applications

IHC, ICC

Field of Research

Scaffold Proteins

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

140 kDa (and smaller due to proteolytic cleavage)

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Rat

WB Brain Quality Control

1

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

RRID

AB_2940003

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