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Anti-Synaptotagmin-6 Antibody

Our Anti-Synaptotagmin-6 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N270/47. It detects human, mouse, and rat Synaptotagmin-6, and is purified by Protein A chromatography. It is great for use in ICC, WB.

Product Specifications

Background

Synaptotagmins are a family of calcium sensing, membrane trafficking proteins. 17 different synaptotagmins have been identified in mammals. Synaptotagmin 6 is thought to be a key component of the secretory machinery involved in acrosomal exocytosis (Michaut M. et al., 2001) .

Short Description

Our Anti-Synaptotagmin-6 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N270/47. It detects human, mouse, and rat Synaptotagmin-6, and is purified by protein a chromatography. It is great for use in WB, ICC, ELISA.

Synonyms

Synaptotagmin-6 (Synaptotagmin VI) (SytVI)

Gene Name

Syt6

UniProt

Q9R0N8

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 246-333 (cytoplasmic C2A domain) of mouse Synaptotagmin-6 (accession number Q9R0N8) produced recombinantly in E. Coli

Target

Synaptotagmin-6

Clonality

Monoclonal

Isotype

IgG1

Clone

N270/47

Type

Primary Antibody

Applications

WB, ICC, ELISA

Field of Research

Vesicle Trafficking/Fusion

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Molecular Weight

55 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Specificity

Does not cross-react with other Synaptotagmins

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Mouse

ICC Quality Control

1

Conjugate

Unconjugated

RRID

AB_11001830

Frequently Asked Questions

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