What is the catalog number for Anti-SUR1 Antibody?

The catalog number for Anti-SUR1 Antibody is 75-267.

What sizes are available for Anti-SUR1 Antibody?

Anti-SUR1 Antibody is available in the following size(s): 100 µL.

Is Anti-SUR1 Antibody in stock?

Anti-SUR1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Anti-SUR1 Antibody

Our Anti-SUR1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N289/16. It is KO validated, detects hamster, mouse, rat SUR1, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Product Specifications

Background

Sulfonylurea receptor 1 (SUR1), or ATP binding cassette transporter subfamily C member 8 is encoded by the gene ABCC8 and is a member of the ABC transporter super family. SUR1 acts to modulate ATP sensitive potassium channels and combines with Kir6.2 (KCNJ11) . SUR1 is involved in insulin release. SUR1 has broad expression in many tissues including brain, heart, pancreas (beta cells) . Diseases associated with this gene include Familial Hyperinsulinemic Hypoglycemia and Diabetes Mellitus.

Short Description

Our Anti-SUR1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N289/16. It is KO validated, detects hamster, mouse, rat SUR1, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, ELISA.

Synonyms

ATP-binding cassette sub-family C member 8 (Sulfonylurea receptor 1)

Gene Name

Abcc8 Sur Sur1

UniProt

Q09429

Host

Mouse

Reactivity

Hamster, Mouse, Rat

Immunogen

Fusion protein amino acids 1548-1582 (LVMVLKRGAILEFDKPEKLLSQKDSVFASFVRADK, cytoplasmic C-terminus) of rat SUR1 (accession number Q09429) produced recombinantly in E. Coli

Target

SUR1

Clonality

Monoclonal

Isotype

IgG1

Clone

N289/16

Type

Primary Antibody

Applications

WB, IHC, ICC, ELISA

Field of Research

Ion Channels and Modulators/Ion Channel Modulators

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Molecular Weight

180 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Specificity

Does not cross-react with SUR2B (based on KO validation results)

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.