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Anti-Clcn4 Antibody FL650 Conjugate

Our Anti-Clcn4 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N222/6. It detects human, mouse, and rat Clcn4, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

Chloride Voltage-Gated Channel 4, CLCN4 or H (+) /Cl (-) exchange transporter 4 is encoded by the gene CLCN4 and is a member of the voltage-gated chloride channel (ClC) family. CLCN4 is a proton-coupled chloride transporter. CLCN4 is expressed in skeletal muscle, brain and heart. Diseases associated with this gene include Raynaud-Claes Syndrome and X-Linked Intellectual Disability Syndrome.

Short Description

Our Anti-Clcn4 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N222/6. It detects human, mouse, and rat Clcn4, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

H (+) /Cl (-) exchange transporter 4 (Chloride channel protein 4) (ClC-4) (Chloride transporter ClC-4)

Gene Name

CLCN4

UniProt

P51793

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Synthetic peptide amino acids 30-51 (TDRHRKITSKSKESIWEFIKSL, cytoplasmic N-terminus) of rat Clcn4 (accession number P51793)

Target

Clcn4

Clonality

Monoclonal

Isotype

IgG1

Clone

N222/6

Type

Primary Antibody

Applications

IHC, ICC

Field of Research

Transporter Proteins

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

85 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

Does not cross-react with Clcn5

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Rat

ICC Quality Control

1

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

RRID

AB_2939943

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