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Anti-TrpV1 Antibody (BSA and Azide free)

Our carrier-free Anti-TrpV1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N221/17. It is KO validated, detects human, mouse, and rat TrpV1, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Product Specifications

Background

Transient receptor potential cation channel subfamily V (vanilloid) member 1, or TrpV1 is a member of transient receptor potential cation channel family (TRP channel) .TrpV1 is a non-selective, ligand activated calcium permeant cation channel that is widely expressed in tissues but elevated in dorsal root ganglia, highly but not solely expressed in postsynaptic dendritic spines. TrpV1 is involved in heat and chemical detection and in pain perception.

Short Description

Our Anti-TrpV1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N221/17. It is KO validated, detects human, mouse, and rat TrpV1, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, ELISA.

Synonyms

Transient receptor potential cation channel subfamily V member 1 (TrpV1) (Capsaicin receptor) (Osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Vanilloid receptor type 1-like)

Gene Name

Trpv1 Vr1 Vr1l

UniProt

O35433

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 1-160 (cytoplasmic N-terminus) of rat TrpV1 (accession number O35433) produced recombinantly in E. Coli

Target

TrpV1

Clonality

Monoclonal

Isotype

IgG1

Clone

N221/17

Type

Primary Antibody

Applications

WB, IHC, ICC, ELISA

Field of Research

Ion Channels and Modulators/Trp Channels

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS

Molecular Weight

100 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and buffer exchanged into 1X PBS. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Rat

WB Brain Quality Control

1

Conjugate

Unconjugated

Frequently Asked Questions

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