Anti-TARPGamma2/4/8 Antibody

Our Anti-TARPGamma2/4/8 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N245/36. It detects mouse and rat TARPGamma2/4/8, and is purified by Protein A chromatography. It is great for use in ICC, WB.

Product Specifications

Background

Voltage-dependent calcium channel gamma-2 subunit, TARPGamma2 or Stargazin is encoded by the gene CACNG2 and is the transmembrane gamma subunit of the L-type calcium channel. Stargazin is in involved in regulation and trafficking of the ligand gated ion channel AMPA receptors. It is thought to play a role in learning and memory. Diseases associated with this gene include forms of deafness, Mental Retardation and childhood absnce epilepsy.

Short Description

Our Anti-TARPGamma2/4/8 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N245/36. It detects mouse and rat TARPGamma2/4/8, and is purified by protein a chromatography. It is great for use in WB, ICC, ELISA.

Synonyms

Voltage-dependent calcium channel gamma-2 subunit (Neuronal voltage-gated calcium channel gamma-2 subunit) (Stargazin) (Transmembrane AMPAR regulatory protein gamma-2) (TARP gamma-2) Voltage-dependent calcium channel gamma-4 subunit (Neuronal voltage-gated calcium channel gamma-4 subunit) (Transmembrane AMPAR regulatory protein gamma-4) (TARP gamma-4) Voltage-dependent calcium channel gamma-8 subunit (Neuronal voltage-gated calcium channel gamma-8 subunit) (Transmembrane AMPAR regulatory protein gamma-8) (TARP gamma-8)

Gene Name

Cacng2 Stg Cacng4 Cacng8

UniProt

Q71RJ2

Host

Mouse

Reactivity

Mouse and Rat

Immunogen

Fusion protein amino acids 203-323 (cytoplasmic C-terminus) of rat TARPGamma2 (accession number Q71RJ2) produced recombinantly in E. Coli

Target

TARPGamma2/4/8

Clonality

Monoclonal

Isotype

IgG2a

Clone

N245/36

Type

Primary Antibody

Applications

WB, ICC, ELISA

Field of Research

Neurotransmitter Receptors

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Molecular Weight

36 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Specificity

Cross-react with TARPGamma4 and TARPGamma8Does not cross-react with TARPGamma3

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.