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Anti-SynCAM4 Antibody FL594 Conjugate

Our Anti-SynCAM4 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N244/5. It is KO validated, detects human, mouse, and rat SynCAM4, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

SynCAM4 cell adhesion molecule, Immunoglobulin Superfamily, Member 4C (IGSF4C), or Nectin-Like Protein 4 (NECL4) is encoded by the gene CADM4 and is a member of the Immunoglobulin-like Cell Adhesion Molecules family. SynCam4 is a cell adhesion molecule involved in many cell processes including the mediation of cell-cell adhesion and assembly, neuronal migration axon growth and differentiation. SynCAM1 is expressed in several tissue types including brain, kidney and liver. Diseases associated with with this gene include Small Intestine Adenocarcinoma.

Short Description

Our Anti-SynCAM4 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N244/5. It is KO validated, detects human, mouse, and rat SynCAM4, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

Cell adhesion molecule 4 (Immunoglobulin superfamily member 4C) (IgSF4C) (Nectin-like protein 4) (NECL-4) (TSLC1-like protein 2)

Gene Name

Cadm4 Igsf4c Necl4 Tsll2

UniProt

Q8R464

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 1-321 (signal peptide and extracellular N-terminus) of mouse SynCAM4 (accession number Q8R464) produced recombinantly in E. Coli

Target

SynCAM4

Clonality

Monoclonal

Isotype

IgG1

Clone

N244/5

Type

Primary Antibody

Applications

IHC, ICC

Field of Research

Cell Adhesion Molecules

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

43 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

Does not cross-react with other SynCAMs (based on KO validation results)

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Mouse

WB Brain Quality Control

1

Conjugate

FL594 Ex: 594 nm, Em: 615 nm

RRID

AB_2939902

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