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Anti-SAPAP1/2 Antibody FL594 Conjugate

Our Anti-SAPAP1/2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N238/31. It detects human, mouse, and rat SAPAP1/2, and is purified by Protein A chromatography. It is great for use in ICC.

Product Specifications

Background

SAPAP1 (also known as disks large associated protein 1) and SAPAP2 (also known as disks large associated protein 2) are members of the SAPAP or DLGAP family of proteins. SAPAP proteins function as scaffolding proteins at excitatory synapses. SAPAP proteins interact with PSD95 family and Shank family proteins to anchor/target neurotransmitter receptors and signaling molecules to the postsynaptic membrane of excitatory synapses.

Short Description

Our Anti-SAPAP1/2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N238/31. It detects human, mouse, and rat SAPAP1/2, and is purified by protein a chromatography. It is great for use in ICC.

Synonyms

Disks large-associated protein 1 (SAPAP1) SAPAP-1 Disks large-associated protein 2 (SAPAP2) SAPAP-2

Gene Name

DLGAP1 DAP1 GKAP DLGAP2 C8orf68 DAP2 ERICH1-AS1

UniProt

P97836

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 772-992 (C-terminus) of rat SAPAP1 (accession number P97836) produced recombinantly in E. Coli

Target

SAPAP1/2

Clonality

Monoclonal

Isotype

IgG1

Clone

N238/31

Type

Primary Antibody

Applications

ICC

Field of Research

Scaffold Proteins

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

110 kDa (varies due to post-translational modifications)

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

Does not cross-react with other SAPAPs

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Rat

WB Brain Quality Control

1

Conjugate

FL594 Ex: 594 nm, Em: 615 nm

RRID

AB_2939858

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