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Anti-QKI-5 Antibody FL650 Conjugate

Our Anti-QKI-5 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N195A/16. It detects human, mouse, and rat QKI-5, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

QKI5 is a member of the Signal Transduction and Activation of RNA proteins (STAR proteins) family. QKI5, QKI6 QKI7 and QKI7b are alternatively spliced mRNAs from the QKI1 gene. QKI5 is a RNA-binding protein. QKI5 has roles in the regulation of splicing, export and stability of mRNA. It is involved in myelinization. It is a nuclear isoform and contains a C-terminal nuclear localization signal. Diseases associated with this gene include Angiocentric Glioma, 6Q Terminal Deletion Syndrome .and Schizophrenia.

Short Description

Our Anti-QKI-5 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N195A/16. It detects human, mouse, and rat QKI-5, and is purified by protein a chromatography. It is great for use in ICC.

Synonyms

Protein quaking (Hqk) (HqkI)

Gene Name

Qki Qk QKI HKQ Qk1 Qka1

UniProt

Q96PU8

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Synthetic peptide amino acids 315-331 (ATKVRRHDMRVHPYQRI, with nuclear localization signal underlined) of human QKI-5 (accession number Q96PU)

Target

QKI-5

Clonality

Monoclonal

Isotype

IgG1

Clone

N195A/16

Type

Primary Antibody

Applications

ICC

Field of Research

Cell Signaling

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

40 kDa (and others)

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

Does not cross-react with QKI-6, QKI-7 or QKI-7bCross-reacts with other STAR proteins containing similar nuclear localization signals

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

WB Brain Quality Control

1

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

RRID

AB_2939847

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