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Anti-Dopamine D2 Receptor Antibody FL650 Conjugate

Our Anti-Dopamine D2 receptor mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N186/29. It detects mouse and rat Dopamine D2 receptor, and is purified by Protein A chromatography. It is great for use in IHC.

Product Specifications

Background

Dopamine D2 receptor is encoded by the gene DRD2. DRD2 is a member of the G-protein coupled receptor 1 family that also includes D1, D3, D4 and D5. This G-protein coupled receptor inhibits adenylyl cyclase activity. DRD2 is expressed in the brain, colon, testis, and skeletal muscle tissue. Diseases associated with DRD2 include cocaine dependence, pathological gambling, and delusional disorder.

Short Description

Our Anti-Dopamine D2 receptor mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N186/29. It detects mouse and rat Dopamine D2 receptor, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

D (2) dopamine receptor (Dopamine D2 receptor)

Gene Name

Drd2

UniProt

P61169

Host

Mouse

Reactivity

Mouse and Rat

Immunogen

Fusion protein amino acids 211-374 (cytoplasmic, long form) of rat Dopamine D2 receptor (accession number P61169) produced recombinantly in E. Coli

Target

Dopamine D2 receptor

Clonality

Monoclonal

Isotype

IgG1

Clone

N186/29

Type

Primary Antibody

Applications

IHC, ICC

Field of Research

Neurotransmitter Receptors

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

50 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

Reacts with both Long and Short formsDoes not cross-react with Dopamine D3 receptor

Quality Control

Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Rat

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

IHC Quality Control

1

RRID

AB_2939839

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