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Anti-Mad3 Antibody FL650 Conjugate

Our Anti-Mad3 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N129A/6. It detects human and mouse Mad3, and is purified by Protein A chromatography. It is great for use in ICC.

Product Specifications

Background

MAX Dimerization Protein 3 is encoded by the gene MXD3. MXD3 is a member of the Myc superfamily. MXD3 is a transcriptional repressor which forms a heterodimer with the cofactor MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. MXD3 is expressed in lung and blood. Diseases associated with MXD3 include Perianal Hematoma and Bartholin's Duct Cyst.

Short Description

Our Anti-Mad3 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N129A/6. It detects human and mouse Mad3, and is purified by protein a chromatography. It is great for use in ICC.

Synonyms

Max dimerization protein 3 (Max dimerizer 3) (Class C basic helix-loop-helix protein 13) (bHLHc13) (Max-associated protein 3) (Max-interacting transcriptional repressor MAD3) (Myx)

Gene Name

MXD3 BHLHC13 MAD3

UniProt

Q9BW11

Host

Mouse

Reactivity

Human and Mouse

Immunogen

Fusion protein amino acids 116-206 (C-terminus) of human Mad3 (accession number Q9BW11) produced recombinantly in E. Coli

Target

Mad3

Clonality

Monoclonal

Isotype

IgG2b

Clone

N129A/6

Type

Primary Antibody

Applications

ICC

Field of Research

Cell Signaling

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

25 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

ICC Quality Control

1

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

RRID

AB_2939831

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