What is the catalog number for Anti-NALCN Antibody?

The catalog number for Anti-NALCN Antibody is 75-220.

What sizes are available for Anti-NALCN Antibody?

Anti-NALCN Antibody is available in the following size(s): 100 µL.

Is Anti-NALCN Antibody in stock?

Anti-NALCN Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Anti-NALCN Antibody

Our Anti-NALCN mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N185/7. It detects mouse and rat NALCN, and is purified by Protein A chromatography. It is great for use in ICC, WB.

Product Specifications

Background

Sodium Leak Channel, Non-Selective is encoded by the gene NALCN. NALCN is a member of the cation-nonselective channel family. NALCN is a voltage-independent, cation-nonselective channel which is permeable to sodium, potassium, and calcium ions. NALCN regulates the resting membrane potential and controls neuronal excitability. NALCN is expressed in the brain, heart, and pancreas. Diseases associated with NALCN include Congenital Contractures of the Limbs and Face, Hypotonia, and Developmental Delay and Hypotonia, Infantile, with Psychomotor Retardation and Characteristic Facies 1.

Short Description

Our Anti-NALCN mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N185/7. It detects mouse and rat NALCN, and is purified by protein a chromatography. It is great for use in WB, ICC, ELISA.

Synonyms

Sodium leak channel non-selective protein (Four domain-type voltage-gated ion channel alpha-1 subunit) (Rb21-channel) (Voltage gated channel-like protein 1)

Gene Name

Nalcn Nca Rb21 Vgcnl1

UniProt

Q6Q760

Host

Mouse

Reactivity

Mouse and Rat

Immunogen

Fusion protein amino acids 1659-1738 (cytoplasmic C-terminus) of rat NALCN (accession number Q6Q760) produced recombinantly in E. Coli

Target

NALCN

Clonality

Monoclonal

Isotype

IgG1

Clone

N185/7

Type

Primary Antibody

Applications

WB, ICC, ELISA

Field of Research

Ion Channels and Modulators/Other Ion Channels

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Molecular Weight

200 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.