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Anti-INPP4b Antibody FL650 Conjugate

Our Anti-INPP4b mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N171/17. It detects human INPP4b, and is purified by Protein A chromatography. It is great for use in ICC.

Product Specifications

Background

Inositol polyphosphate 4-phosphatase type II is encoded by the gene INPP4B. INPP4B is a member of the inositol 3,4-bisphosphate 4-phosphatase family. INPP4B is an enzyme involved in phosphatidylinositol pathways. This enzyme catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-triphosphate, and inositol 3,4-triphosphate. The lipid phosphatase activity is critical for tumor suppressor function. INPP4B activity modulates cell cycle progression and cell survival. INPP4B is widely expressed with the highest levels occuring in the skeletal muscle and heart. No disorders were found to be associated with INPP4B.

Short Description

Our Anti-INPP4b mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N171/17. It detects human and mouse INPP4b, and is purified by protein a chromatography. It is great for use in ICC.

Synonyms

Type II inositol 3,4-bisphosphate 4-phosphatase (EC 3.1.3.66) (Inositol polyphosphate 4-phosphatase type II)

Gene Name

INPP4B

UniProt

O15327

Host

Mouse

Reactivity

Human and Mouse

Immunogen

Fusion protein amino acids 395-518 of human INPP4b (accession number O15327) produced recombinantly in E. Coli

Target

INPP4b

Clonality

Monoclonal

Isotype

IgG1

Clone

N171/17

Type

Primary Antibody

Applications

ICC

Field of Research

Cell Signaling

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

100 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

Does not cross-react with INPP4a

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

ICC Quality Control

1

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

RRID

AB_2939807

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