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Anti-Neurexin-1-Beta (Staining) Antibody (BSA and Azide free)

Our carrier-free Anti-Neurexin-1-Beta (staining) mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N170A/1. It detects human and mouse Neurexin-1-Beta (staining), and is purified by Protein A chromatography. It is great for use in ICC, WB.

Product Specifications

Background

Neurexin-1Beta is a member of the neurexin family. Neurexin-1Beta is a membrane bound receptor and binds neuroligins and forms complexes at neuronal synapses in the central nervous system. Binding parterns for Neurexin 1beta include CASK, Neuroligins 1-3 and DAG1. Neurexin-1Beta serves as a presynaptic marker and plays an important role in assembling presynaptic and postsynaptic machinery. This protein may be involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins and possibly plays a role in synaptic junctions formation or maintenance.

Short Description

Our Anti-Neurexin-1-Beta (staining) mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N170A/1. It detects human and mouse Neurexin-1-Beta (staining), and is purified by protein a chromatography. It is great for use in WB, ICC, ELISA.

Synonyms

Neurexin-1-beta (Neurexin I-beta)

Gene Name

NRXN1

UniProt

P58400

Host

Mouse

Reactivity

Human and Mouse

Immunogen

Synthetic peptide amino acids 47-64 (ASSLGAHHIHHFHGSSKH, extracellular N-terminus) of rat Neurexin-1-Beta (accession number Q63373)

Target

Neurexin-1-Beta (staining)

Clonality

Monoclonal

Isotype

IgG1

Clone

N170A/1

Type

Primary Antibody

Applications

WB, ICC, ELISA

Field of Research

Cell Adhesion Molecules/ Cell Markers/Neuronal Markers/Synapse Markers/Pre-synaptic Markers

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS

Molecular Weight

50 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and buffer exchanged into 1X PBS. Purified mAbs are >90% specific antibody.

Specificity

Does not cross-react with Neurexin-2-Beta

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Rat

ICC Quality Control

1

Conjugate

Unconjugated

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