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Anti-Pannexin-2 Antibody FL550 Conjugate

Selected Variant

75-213-FL550

Size: 200 µL

Our Anti-Pannexin-2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N121A/31. It detects rat Pannexin-2, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

Pannexin 2 is encoded by the gene PANX2. PANX2 is a member of the pannexin family. PANX2 combines with pannexin 1 to form cell type-specific gap junctions with distinct properties. PANX2 is expressed in the eye, thyroid, prostate, kidney, liver, and central nervous system. Diseases associated with PANX2 include Oculodentodigital Dysplasia and Chronic Closed-Angle Glaucoma.

Short Description

Our Anti-Pannexin-2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N121A/31. It detects rat Pannexin-2, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

Pannexin-2

Gene Name

Panx2 Px2

UniProt

P60571

Host

Mouse

Reactivity

Rat

Immunogen

Fusion protein amino acids 11-664 (all but first 10 amino acids, encompassing extracellular and cytoplasmic domains) of rat Pannexin-2 (accession number P60571) produced recombinantly in E. Coli

Target

Pannexin-2

Clonality

Monoclonal

Isotype

IgG1

Clone

N121A/31

Type

Primary Antibody

Applications

IHC, ICC

Field of Research

Ion Channels and Modulators/Other Ion Channels

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

70 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

Does not cross-react with Pannexin-1 or Pannexin-3

Quality Control

Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Rat

Conjugate

FL550 Ex: 550 nm, Em: 575 nm

IHC Quality Control

1

RRID

AB_2939789

Price

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