What is the catalog number for Anti-Gs Protein, Alpha Subunit Antibody?

The catalog number for Anti-Gs Protein, Alpha Subunit Antibody is 75-211.

What sizes are available for Anti-Gs Protein, Alpha Subunit Antibody?

Anti-Gs Protein, Alpha Subunit Antibody is available in the following size(s): 100 µL.

Is Anti-Gs Protein, Alpha Subunit Antibody in stock?

Anti-Gs Protein, Alpha Subunit Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Anti-Gs Protein, Alpha Subunit Antibody

Our Anti-Gs protein, alpha subunit mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N192/12. It detects mouse and rat Gs protein, alpha subunit, and is purified by Protein A chromatography. It is great for use in ICC, WB.

Product Specifications

Background

Guanine nucleotide-binding protein G (s) subunit alpha isoforms short or Gs protein α subunit is encoded by the gene GNAS. Gsα is one of three subunits that make up a guanine nucleotide binding protein (Gprotein) . The other proteins are a beta and a gamma subunit. G proteins are further divided into families depending on the type of α subunit included, G (S) alpha, G (Q) alpha, G (I) alpha, and G (12) alpha. Gsα functions as a transducer of numerous signaling pathways that are controlled by g protein coupled receptors (GPCRs) by coupling receptors to adenylyl cyclase and results in increased levels of the signaling molecule cAMP. Diseases associated with GNAS include Mccune-Albright Syndrome and Progressive Osseous Heteroplasia.

Short Description

Our Anti-Gs protein, alpha subunit mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N192/12. It detects mouse and rat Gs protein, alpha subunit, and is purified by protein a chromatography. It is great for use in WB, ICC, ELISA.

Synonyms

Guanine nucleotide-binding protein G (s) subunit alpha isoforms short (Adenylate cyclase-stimulating G alpha protein)

Gene Name

GNAS GNAS1

UniProt

P04896-2

Host

Mouse

Reactivity

Mouse and Rat

Immunogen

Fusion protein amino acids 1-380 (full-length, short form) of bovine Gs protein alpha subunit (accession number P04896-2) produced recombinantly in E. Coli

Target

Gs protein, alpha subunit

Clonality

Monoclonal

Isotype

IgG1

Clone

N192/12

Type

Primary Antibody

Applications

WB, ICC, ELISA

Field of Research

Cell Signaling/G Protein Signaling

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Molecular Weight

45 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Specificity

Reacts with both Active and Inactive/QL forms

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.