Anti-MGL Antibody

Our Anti-MGL mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N90/20. It detects mouse and rat MGL, and is TC supernatant. It is great for use in ICC, WB.

Product Specifications

Background

Monoglyceride lipase, HU-K5 , MAGL or MGL is encoded by the gene MGLL. MGL acts as a serine hydrolase of the AB hydrolase superfamily. This enzyme catalyzes the conversion of monoacylglycerides to free fatty acids and glycerol and is involved in physiological processes including pain and nociperception through hydrolysis of the endocannabinoid 2-arachidonoylglycerol. (PubMed:19029917, PubMed:20079333, PubMed:21049984, PubMed:22969151, PubMed:24368842) . MGL is found ubiquitously and highly expressed in adipose tissue, adrenal gland, ovary, heart, spleen, lung, skeletal muscle, kidney and brain. Diseases associated with this gene include Cannabis Dependence and Hallucinogen Dependence.

Short Description

Our Anti-MGL mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N90/20. It detects mouse and rat MGL, and is tc supernatant. It is great for use in WB, ICC, ELISA.

Synonyms

Monoglyceride lipase (MGL) (EC 3.1.1.23) (Monoacylglycerol lipase) (MAGL)

Gene Name

Mgll Mgl2

UniProt

Q8R431

Host

Mouse

Reactivity

Mouse and Rat

Immunogen

Synthetic peptide amino acids 1-16 (MPEASSPRRTPQNVPY, N-terminus) of rat MGL (accession number Q8R431)

Target

MGL

Clonality

Monoclonal

Isotype

IgG2b

Clone

N90/20

Type

Primary Antibody

Applications

WB, ICC, ELISA

Field of Research

Cell Signaling

Concentration

Lot dependent

Format

TC Supernatant

Buffer

Supernatant is provided in cell culture medium with 0.1% sodium azide as anti-microbial

Molecular Weight

35 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.