Anti-Cav3.1 Ca2+ Channel Antibody FL650 Conjugate

Voltage-dependent T-type calcium channel subunit alpha or Cav3.1 Ca2+ channel is encoded by the gene CACNA1G. Cav3.1 is a pore forming alpha subunit of T voltage-sensitive calcium channels and gives rise to T-type calcium currents. (transient opening calcium channels) . These channels facilitate entry of calcium ions into excitable cells are involved in a variety of calcium dependent processes, including neurotransmitter release, muscle contraction, and gene expression. Cav3.1 is expressed in various tissues including heart and smooth muscle, kidney, bone, and brain as a membrane bound protein. Diseases associated with this gene include forms of Spinocerebellar Ataxia

Our Anti-Cav3.1 Ca2+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N178A/9. It is KO validated, detects human, mouse, and rat Cav3.1 Ca2+ channel, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.