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Anti-PARIS/ZNF746 Antibody

Our Anti-PARIS/ZNF746 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N196/16. It detects human, mouse, and rat PARIS/ZNF746, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Product Specifications

Background

Zinc finger protein 746, Parkin-Interacting Substrate or PARIS/ZNF746 is encoded by the gene ZNF746. PARIS is a transcription repressor that binds to a consensus sequence on promoters and represses the expression of a transcriptional coactivator, PGC-1-alpha (PPARGC1A) . This protein plays a role in regulation of neuron death. PARIS is found in the cytoplasm and nucleus

Short Description

Our Anti-PARIS/ZNF746 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N196/16. It detects human, mouse, and rat PARIS/ZNF746, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, ELISA.

Synonyms

Zinc finger protein 746 (Parkin-interacting substrate) (PARIS)

Gene Name

ZNF746 PARIS

UniProt

Q6NUN9

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 1-322 (N-terminus) of human ZNF746 (accession number Q6NUN9) produced recombinantly in E. Coli

Target

PARIS/ZNF746

Clonality

Monoclonal

Isotype

IgG1

Clone

N196/16

Type

Primary Antibody

Applications

WB, IHC, ICC, ELISA

Field of Research

Transcription Regulation

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.123

Molecular Weight

60-70 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Specificity

Does not cross-react with ZNF783 or ZNF398

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

WB Brain Quality Control

1

Conjugate

Unconjugated

RRID

AB_10674714

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