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Anti-Tauro-GM2 Antibody

Our Anti-Tauro-GM2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N175/9. It detects Tauro-GM2, and is purified by Protein A chromatography. It is great for use in ELISA.

Product Specifications

Background

References for this antibody can be found in the study: Presence of an unusual GM2 derivative, taurine-conjugated GM2, in Tay-Sachs brain. The Journal of Biological Chemistry, 25 Jun 2003, 278 (37) :35286-35291 DOI: 10.1074/jbc.m306126200 PMID: 12829702 2003 Li et al

Short Description

Our Anti-Tauro-GM2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N175/9. It detects n/a Tauro-GM2, and is purified by protein a chromatography. It is great for use in ICC, ELISA.

Host

Mouse

Immunogen

Taurine-conjugated GM2 ganglioside (tauro-GM2) as prepared chemically in 2003 Li et al J BiolChem (PMID 12829702, GM2 in dimethylformamide stirred with taurine, diethyl phosphorocyanidateand triethylamine at room temperature for 5 h, reaction stopped with KCl, mixture passed through solid-phase extraction cartridge, unabsorbed materials washed by water and absorbed materialseluted with methanol and further purified by high performance anion-exchange chromatography) .

Target

Tauro-GM2

Clonality

Monoclonal

Isotype

IgM

Clone

N175/9

Type

Primary Antibody

Applications

ICC, ELISA

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.119

Molecular Weight

1.3 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity against unconjugated GM2

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Conjugate

Unconjugated

RRID

AB_11001847

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