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Anti-JMJD2A Antibody FL550 Conjugate

Our Anti-JMJD2A mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N154/32. It detects human JMJD2A, and is purified by Protein A chromatography. It is great for use in ICC.

Product Specifications

Background

Lysine Demethylase 4A is encoded by the gene KDM4A. KDM4A is a member of the JHDM3 histone demethylase family. KDM4A is a nuclear protein that contains a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. KDM4A functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor. KDM4A is expressed is several organs with the highest expression in the lungs. Diseases associated with KDM4A include Attention Deficit-Hyperactivity Disorder.

Short Description

Our Anti-JMJD2A mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N154/32. It detects human JMJD2A, and is purified by protein a chromatography. It is great for use in ICC.

Synonyms

Lysine-specific demethylase 4A (EC 1.14.11.-) (JmjC domain-containing histone demethylation protein 3A) (Jumonji domain-containing protein 2A)

Gene Name

KDM4A JHDM3A JMJD2 JMJD2A KIAA0677

UniProt

O75164

Host

Mouse

Reactivity

Human

Immunogen

Fusion protein amino acids 568-674 of human JMJD2A (accession number O75164) produced recombinantly in E. Coli

Target

JMJD2A

Clonality

Monoclonal

Isotype

IgG1

Clone

N154/32

Type

Primary Antibody

Applications

ICC

Field of Research

Epigenetics

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

120 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

Does not cross-react with JMJD2C

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

ICC Quality Control

1

Conjugate

FL550 Ex: 550 nm, Em: 575 nm

RRID

AB_2939701

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