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Anti-Ankyrin-G (Blotting) Antibody FL594 Conjugate

Selected Variant

75-187-FL594

Size: 200 µL

Our Anti-Ankyrin-G (Blotting) mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N106/20. It detects human, mouse, and rat Ankyrin-G (Blotting), and is purified by Protein A chromatography. It is great for use in ICC.

Product Specifications

Background

Ankyrin-G (ankyrin 3) is a member of the Ankyrin family which consists of Ankyrin R (1), Ankyrin B (2) and Ankyrin G (3) all of which are expressed in the nervous system. Ankyrins are structural proteins that aid in the attachment of integral membrane proteins with the spectrin-actin cytoskeleton, and thus targets voltage-gated sodium channels, potassium channels, cell adhesion molecules and others at the nodes of Ranvier and axonal initial segments (AIS) . Variants in Ankyrin G have been linked to bipolar disorder.

Short Description

Our Anti-Ankyrin-G (Blotting) mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N106/20. It detects human, mouse, non-human primate, and rat Ankyrin-G (Blotting), and is purified by protein a chromatography. It is great for use in ICC.

Synonyms

Ankyrin-3 (ANK-3) (Ankyrin-G)

Gene Name

ANK3

UniProt

E9PE32

Host

Mouse

Reactivity

Human, Mouse, Non-Human Primate, and Rat

Immunogen

Fusion protein ~1000 amino acids of Ankyrin-G (accession number E9PE32) produced recombinantly in E. Coli

Target

Ankyrin-G (Blotting)

Clonality

Monoclonal

Isotype

IgG1

Clone

N106/20

Type

Primary Antibody

Applications

ICC

Field of Research

Axonal Markers/Scaffold Proteins

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

>200 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

WB Brain Quality Control

1

Conjugate

FL594 Ex: 594 nm, Em: 615 nm

RRID

AB_2939694

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