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Anti-Gamma-Protocadherin-B2 Antibody

Our Anti-Gamma-protocadherin-B2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N148/30. It is KO validated, detects mouse Gamma-protocadherin-B2, and is purified by Protein A chromatography. It is great for use in ICC, WB.

Product Specifications

Background

Protocadherin Gamma Subfamily B, 2 is encoded by the gene PCDHGB2. PCDHGB2 is a member of the protocadherin gamma gene cluster. PCDHGB2 is a neural cadherin-like cell adhesion protein that most likely plays a critical role in the establishment and function of specific cell-cell connections in the brain. PCDHGB2 is expressed in the nervous system. Diseases associated with PCDHGB2 include Prune Belly Syndrome.

Short Description

Our Anti-Gamma-protocadherin-B2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N148/30. It is KO validated, detects mouse Gamma-protocadherin-B2, and is purified by protein a chromatography. It is great for use in WB, ICC, ELISA.

Synonyms

Protocadherin gamma B2 (Protocadherin gamma subfamily B, 2)

Gene Name

Pcdhgb2

UniProt

Q91XX7

Host

Mouse

Reactivity

Mouse

Immunogen

Fusion protein amino acids 719-804 (variable cytoplasmic domain) of mouse Gamma-protocadherin-B2 (accession number Q91XX7) produced recombinantly in E. Coli

Target

Gamma-protocadherin-B2

Clonality

Monoclonal

Isotype

IgG1

Clone

N148/30

Type

Primary Antibody

Applications

WB, ICC, ELISA

Field of Research

Cell Adhesion Molecules

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.112

Molecular Weight

100 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity against other Gamma-protocadherin-A, -B or -C proteins

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Mouse

ICC Quality Control

1

Conjugate

Unconjugated

RRID

AB_10675142

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