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Anti-LRP4 (Cytoplasmic) Antibody

Our Anti-LRP4 (cytoplasmic) mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N164/6. It detects mouse and rat LRP4 (cytoplasmic), and is purified by Protein A chromatography. It is great for use in ICC, WB.

Product Specifications

Background

Low-density lipoprotein receptor-related protein 4 or LRP4 is encoded by the gene LRP4. And is a member of the low-density lipoprotein receptor-related protein family. Proteins in this family function in a wide range of physiological processes, including the regulation of lipid metabolism, protection against atherosclerosis, neurodevelopment. LRP4 may be involved in the negative regulation of the canonical Wnt signaling pathway. LRP4 is expressed in bone and several regions of the brain. Mutations in this gene are associated with Cenani-Lenz syndrome.

Short Description

Our Anti-LRP4 (cytoplasmic) mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N164/6. It detects mouse and rat LRP4 (cytoplasmic), and is purified by protein a chromatography. It is great for use in WB, ICC, ELISA.

Synonyms

Low-density lipoprotein receptor-related protein 4 (LRP-4) (LDLR dan)

Gene Name

Lrp4 Kiaa0816

UniProt

Q8VI56

Host

Mouse

Reactivity

Mouse and Rat

Immunogen

Fusion protein amino acids 1747-1905 (cytoplasmic C-terminus) of mouse LRP4 (accession number Q8VI56) produced recombinantly in E. Coli

Target

LRP4 (cytoplasmic)

Clonality

Monoclonal

Isotype

IgG1

Clone

N164/6

Type

Primary Antibody

Applications

WB, ICC, ELISA

Field of Research

Cell Signaling/Wnt Signaling

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.110

Molecular Weight

215 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Mouse

WB Brain Quality Control

1

Conjugate

Unconjugated

RRID

AB_2139028

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