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Anti-Olig1 Antibody

Our Anti-Olig1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N149/25. It detects mouse Olig1, and is purified by Protein A chromatography. It is great for use in ICC, WB.

Product Specifications

Background

Oligodendrocyte transcription factor 1, Basic Domain, Helix-Loop-Helix Protein, Class B, 6 or Class E Basic Helix-Loop-Helix Protein 21 is encoded by the gene Olig1. Olig1 is a transcription factor and a member of the basic helix-loop-helix (bHLH) factor family. Olig1 promotes formation and maturation of oligodendrocytes (oligodendrogensis) . Olig1 is expressed in spinal cord and brain during development, and by oligodendrocytes after late embryonic development. Olig1 is a useful marker for Oligodendrocyte staining. Diseases associated with this gene include Oligodendroglioma and Grade Iii Astrocytoma.

Short Description

Our Anti-Olig1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N149/25. It detects mouse Olig1, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, ELISA.

Synonyms

Oligodendrocyte transcription factor 1 (Oligo1) (Oligodendrocyte-specific bHLH transcription factor 1)

Gene Name

Olig1

UniProt

Q9JKN5

Host

Mouse

Reactivity

Mouse

Immunogen

Fusion protein amino acids 1-67 (N-terminus) of mouse Olig1 (accession number Q9JKN5) produced recombinantly in E. Coli

Target

Olig1

Clonality

Monoclonal

Isotype

IgG1

Clone

N149/25

Type

Primary Antibody

Applications

WB, IHC, ICC, ELISA

Field of Research

Glial and Schwann Cell Markers/Astrocyte Markers/Oligodendrocyte Markers/Neurogenesis and Development/Transcription Regulation

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.108

Molecular Weight

30 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity against Olig2

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Mouse

ICC Quality Control

1

Conjugate

Unconjugated

RRID

AB_2157532

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