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Anti-Gamma-Protocadherin-A3 Antibody FL550 Conjugate

Our Anti-Gamma-protocadherin-A3 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N144/17. It is KO validated, detects mouse Gamma-protocadherin-A3, and is purified by Protein A chromatography. It is great for use in ICC.

Product Specifications

Background

Protocadherin gamma A3 is encoded by the gene Pcdhga3. Gamma-protocadherins belong to a superfamily of homophilic cell-adhesion proteins. These cell adhesion proteins are thought to be involved in establishing and function of cell-cell connections in brain. Gamma-Protocadherin-A3 is a type I transmembrane receptor and is a calcium-dependent cell-adhesion protein. Gamma-Protocadherin-A3 plays a role in the establishment and maintenance of specific neuronal connections in the brain. Gamma-Protocadherin-A3 is expressed in the central nervous system where it localizes to synapses. Diseases associated with this gene include Pineal Gland Cancer.

Short Description

Our Anti-Gamma-protocadherin-A3 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N144/17. It is KO validated, detects mouse Gamma-protocadherin-A3, and is purified by protein a chromatography. It is great for use in ICC.

Synonyms

Protocadherin gamma A3 (Protocadherin gamma subfamily A, 3)

Gene Name

Pcdhga3

UniProt

Q91XY5

Host

Mouse

Reactivity

Mouse

Immunogen

Fusion protein amino acids 720-804 (variable cytoplasmic domain) of mouse Gamma-protocadherin-A3 (accession number Q91XY5) produced recombinantly in E. Coli

Target

Gamma-protocadherin-A3

Clonality

Monoclonal

Isotype

IgG1

Clone

N144/17

Type

Primary Antibody

Applications

ICC

Field of Research

Cell Adhesion Molecules

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

100 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity against other Gamma-protocadherin-A, -B or -C proteins

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Mouse

ICC Quality Control

1

Conjugate

FL550 Ex: 550 nm, Em: 575 nm

RRID

AB_2939653

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