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Anti-GRK6A/B Antibody

Our Anti-GRK6A/B mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N142/28. It detects mouse GRK6A/B, and is purified by Protein A chromatography. It is great for use in ICC, WB.

Product Specifications

Background

G-protein coupled receptor kinase 6 is encoded by the gene GRK6. GRK6 is a member of the protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily. GRK6 phosphorylates the activated forms of G-protein coupled receptors, thus initiating their deactivation. GRK6 is expressed in the brain in striatal neurons and spleen. No disorders were found to be associated with GRK6.

Short Description

Our Anti-GRK6A/B mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N142/28. It detects mouse GRK6A/B, and is purified by protein a chromatography. It is great for use in WB, ICC, ELISA.

Synonyms

G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK6)

Gene Name

Grk6 Gprk6

UniProt

O70293

Host

Mouse

Reactivity

Mouse

Immunogen

Fusion protein amino acids 371-576 (C-terminus) of mouse GRK6A (accession number O70293) produced recombinantly in E. Coli

Target

GRK6A/B

Clonality

Monoclonal

Isotype

IgG1

Clone

N142/28

Type

Primary Antibody

Applications

WB, ICC, ELISA

Field of Research

Cell Signaling/G Protein Signaling

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.104

Molecular Weight

65 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Specificity

Cross-reacts with GRK6B

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Mouse

ICC Quality Control

1

Conjugate

Unconjugated

RRID

AB_2115469

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