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Anti-CDY1/2 Antibody

Our Anti-CDY1/2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N143/38. It detects human CDY1/2, and is purified by Protein A chromatography. It is great for use in ICC, WB.

Product Specifications

Background

This antibody recognizes the proteins Testis-specific chromodomain protein Y 1 and 2 and are encoded by the genes CDY1 and CDY2A respectively. These genes each have a paralog (CDY1B and CDY2B) which are also present on the Y chromosome. Proteins in the CDY-related family contain a chromodomain, involved in chromatin binding, and a histone acetyltransferase catalytic domain. These proteins are expressed in the nucleaus in testis. Diseases associated with these genes include Y-Linked Spermatogenic Failure, and Y Chromosome Infertility.

Short Description

Our Anti-CDY1/2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N143/38. It detects human CDY1/2, and is purified by protein a chromatography. It is great for use in WB, ICC, ELISA.

Synonyms

Testis-specific chromodomain protein Y 1 (EC 2.3.1.48)

Gene Name

CDY1 CDY1A; CDY1B

UniProt

Q9Y6F8

Host

Mouse

Reactivity

Human

Immunogen

Fusion protein amino acids 6-66 (Chromo domain) of human CDY1 (accession number Q9Y6F8) produced recombinantly in E. Coli

Target

CDY1/2

Clonality

Monoclonal

Isotype

IgG1

Clone

N143/38

Type

Primary Antibody

Applications

WB, ICC, ELISA

Field of Research

Epigenetics

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.102

Molecular Weight

60 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity against CDYL1 or CDYL2

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

ICC Quality Control

1

Conjugate

Unconjugated

RRID

AB_10673274

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