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Anti-RGS14 Antibody FL594 Conjugate

Our Anti-RGS14 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N133/21. It is KO validated, detects mouse and rat RGS14, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

RGS14 is a member of the RGS family (regulator of G-protein signaling) and is highly expressed in the prefrontal cortex. Hallmark domains of RGS14 include a RGS domain, two Raf-like Ras-binding domains and a GoLoco motif. RGS14 inactivates G protein α subunits. Alterations in this protein have been implicated in Schizophrenia and Alzheimer’s disease.

Short Description

Our Anti-RGS14 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N133/21. It is KO validated, detects mouse and rat RGS14, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

Regulator of G-protein signaling 14 (RGS14)

Gene Name

Rgs14

UniProt

O08773

Host

Mouse

Reactivity

Mouse and Rat

Immunogen

Fusion protein amino acids 1-544 (full-length) of rat RGS14 (accession number O08773) produced recombinantly in E. Coli

Target

RGS14

Clonality

Monoclonal

Isotype

IgG2a

Clone

N133/21

Type

Primary Antibody

Applications

IHC, ICC

Field of Research

Cell Signaling/Scaffold Proteins

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

60 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

Does not react with RGS12

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Rat

WB Brain Quality Control

1

Conjugate

FL594 Ex: 594 nm, Em: 615 nm

RRID

AB_2939626

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