(±) -Nornicotine-d4
(±) -Nornicotine-d4 is the deuterium labeled (±) -Nornicotine. (±) -Nornicotine is a major metabolite of Nicotine. (±) -Nornicotine is a partial nAChRs agonist, specifically activating receptor subtypes containing α7 and α6 subunits. (±) -Nornicotine disrupts β-catenin and ZO-1, and induces F-actin depolymerization. (±) -Nornicotine supports self-administration behavior. (±) -Nornicotine can be used in the research of atherosclerosis, Alzheimer's disease, and schizophrenia[1][2][3][4][5].
Product Specifications
CAS Number
66148-18-3
Product Name Alternative
Nornicotine-d4
UNSPSC
12352005
Hazard Statement
H301, H311, H315, H319, H331, H335
Target
Drug Metabolite; Endogenous Metabolite; Isotope-Labeled Compounds; nAChR; β-catenin
Type
Isotope-Labeled Compounds
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others; Stem Cell/Wnt
Field of Research
Neurological Disease; Cardiovascular Disease
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
[2H]C1=C(C2NCCC2)C([2H])=C([2H])C([2H])=N1
Molecular Formula
C9H8D4N2
Molecular Weight
152.23
Precautions
H301, H311, H315, H319, H331, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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