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Anti-JIP-2/IB-2 Antibody FL594 Conjugate

Our Anti-JIP-2/IB-2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N135/37. It is KO validated, detects mouse and rat JIP-2/IB-2, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

Mitogen-activated protein kinase 8 interacting protein 2 is encoded by the gene MAPK8IP2. MAPK8IP2 is a member of the JIP scaffold family. MAPK8IP2 is a scaffold protein that is involved in the regulation of the c-Jun amino-terminal kinase signaling pathway. MAPK8IP2 has been shown to interact with and regulate the activity of MAPK8/JNK1 and MAP2K7/MKK7 kinases. MAPK8IP2 is expressed in the brain and testis. Diseases associated with MAPK8IP2 include Cervical Verrucous Carcinoma and Isthmus Cancer.

Short Description

Our Anti-JIP-2/IB-2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N135/37. It is KO validated, detects mouse and rat JIP-2/IB-2, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

C-Jun-amino-terminal kinase-interacting protein 2 (JIP-2) (JNK-interacting protein 2) (Islet-brain-2) (IB-2) (JNK MAP kinase scaffold protein 2) (Mitogen-activated protein kinase 8-interacting protein 2)

Gene Name

Mapk8ip2 Ib2 Jip2

UniProt

Q9ERE9

Host

Mouse

Reactivity

Mouse and Rat

Immunogen

Fusion protein amino acids 226-421 of mouse JIP-2/IB-2 (accession number Q9ERE9) produced recombinantly in E. Coli

Target

JIP-2/IB-2

Clonality

Monoclonal

Isotype

IgG1

Clone

N135/37

Type

Primary Antibody

Applications

IHC, ICC

Field of Research

Cell Signaling

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

90 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

Does not react with JIP-1

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Mouse

WB Brain Quality Control

1

Conjugate

FL594 Ex: 594 nm, Em: 615 nm

RRID

AB_2939606

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