Anti-Haspin/GSG2 Antibody FL490 Conjugate

Histone H3 Associated Protein Kinase is encoded by the gene HASPIN. HASPIN is a member of the protein kinase superfamily, Ser/Thr protein kinase family, and the Haspin subfamily. HASPIN is a serine/threonine - protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. HASPIN may act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment, and normal progression through the cell cycle. HASPIN is expressed in the testis, thymus, bone marrow, prostate, intestine, lung, spleen, and lymph node. No diseases were found to be associated with HASPIN.

Our Anti-Haspin/GSG2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N128A/2. It detects human Haspin/GSG2, and is purified by protein a chromatography. It is great for use in ICC.

Serine/threonine-protein kinase haspin (EC 2.7.11.1) (Germ cell-specific gene 2 protein) (H-haspin) (Haploid germ cell-specific nuclear protein kinase)

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.