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Anti-Haspin/GSG2 Antibody

Our Anti-Haspin/GSG2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N128A/2. It detects human Haspin/GSG2, and is purified by Protein A chromatography. It is great for use in ICC, IP, WB.

Product Specifications

Background

Histone H3 Associated Protein Kinase is encoded by the gene HASPIN. HASPIN is a member of the protein kinase superfamily, Ser/Thr protein kinase family, and the Haspin subfamily. HASPIN is a serine/threonine - protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. HASPIN may act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment, and normal progression through the cell cycle. HASPIN is expressed in the testis, thymus, bone marrow, prostate, intestine, lung, spleen, and lymph node. No diseases were found to be associated with HASPIN.

Short Description

Our Anti-Haspin/GSG2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N128A/2. It detects human Haspin/GSG2, and is purified by protein a chromatography. It is great for use in WB, ICC, IP, ELISA.

Synonyms

Serine/threonine-protein kinase haspin (EC 2.7.11.1) (Germ cell-specific gene 2 protein) (H-haspin) (Haploid germ cell-specific nuclear protein kinase)

Gene Name

HASPIN GSG2

UniProt

Q8TF76

Host

Mouse

Reactivity

Human

Immunogen

Fusion protein amino acids 1-798 (full-length) of human Haspin (accession number Q8TF76)

Target

Haspin/GSG2

Clonality

Monoclonal

Isotype

IgG1

Clone

N128A/2

Type

Primary Antibody

Applications

WB, ICC, IP, ELISA

Field of Research

Epigenetics

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.87

Molecular Weight

90 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

ICC Quality Control

1

Conjugate

Unconjugated

RRID

AB_2114890

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