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Anti-Neuroligin-1 Antibody FL650 Conjugate

Our Anti-Neuroligin-1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N97A/31. It is KO validated, detects mouse and rat Neuroligin-1, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

Neuroligin 1 is a member of a large family of alternatively sliced proteins located at the post synaptic surface in the central nervous system, and stains as a post synaptic marker. Neuroligin 1 is involved in cell-cell-interactions by binding to neurexin family members and other postsynaptic proteins to localize receptors and channels in the postsynaptic density. Suggested roles for Neuroligin 1 include synapse function and synaptic signal transmission and maintaining synapse integrity. Mutations in Neuroligans have been implicated in autism and other cognitive disorders.

Short Description

Our Anti-Neuroligin-1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N97A/31. It is KO validated, detects chicken, human, mouse, and rat Neuroligin-1, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

Neuroligin-1 (Neuroligin I)

Gene Name

Nlgn1

UniProt

Q62765

Host

Mouse

Reactivity

Chicken, Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 718-843 (intracellular C-terminus) of rat Neuroligin-1 (accession number NP_446320) produced recombinantly in E. Coli

Target

Neuroligin-1

Clonality

Monoclonal

Isotype

IgG1

Clone

N97A/31

Type

Primary Antibody

Applications

IHC, ICC

Field of Research

Cell Adhesion Molecules/ Cell Markers/Neuronal Markers/Synapse Markers/Post-synaptic Markers

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

120 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

Does not cross-react with Neuroligin-2, -3, -4 or -4*

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Rat

WB Brain Quality Control

1

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

RRID

AB_2939595

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