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Anti-Neuroligin-3 Antibody FL490 Conjugate

Our Anti-Neuroligin-3 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N110/29. It is KO validated, detects human and mouse Neuroligin-3, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

Neuroligin3 is encoded by the gene NLGN3. Neuroligin3 is a transmembrane scaffolding protein and cell adhesion molecule. It is involved in cell-cell interactions in neurons and in other cell types. It is expressed in many tissues, including the brain where it is located at the postysynaptic membrane and is involved in regulation of excitatory synapses, synapse formation and synaptic transmission. Mutations in this gene may be associated with autism and Asperger syndrome.

Short Description

Our Anti-Neuroligin-3 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N110/29. It is KO validated, detects human, mouse, and rat Neuroligin-3, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

Neuroligin-3 (Gliotactin homolog)

Gene Name

Nlgn3

UniProt

AAA97871

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 730-848 (intracellular C-terminus) of rat Neuroligin-3 (accession number AAA97871) produced recombinantly in E. Coli

Target

Neuroligin-3

Clonality

Monoclonal

Isotype

IgG1

Clone

N110/29

Type

Primary Antibody

Applications

IHC, ICC

Field of Research

Cell Adhesion Molecules/ Cell Markers/Neuronal Markers/Synapse Markers/Post-synaptic Markers

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

110 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

Does not cross-react with Neuroligin-1, -2, -4 or -4*

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Rat

WB Brain Quality Control

1

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

RRID

AB_2939584

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