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Anti-MPP8 Antibody FL594 Conjugate

Our Anti-MPP8 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N119/44. It detects human MPP8, and is purified by Protein A chromatography. It is great for use in ICC.

Product Specifications

Background

M-Phase Phosphoprotein 8 is encoded by the gene MPHOSPH8. MPHOSPH8 is a heterochromatin component that specifically recognizes and binds methylated 'Lys-9' of histone H3 (H3K9me) and promotes recruitment of proteins that mediate epigenetic repression. MPHOSPH8 is expressed in the brain. Diseases associated with MPHOSPH8 include Charcot-Marie-Tooth Disease.

Short Description

Our Anti-MPP8 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N119/44. It detects human MPP8, and is purified by protein a chromatography. It is great for use in ICC.

Synonyms

M-phase phosphoprotein 8 (Two hybrid-associated protein 3 with RanBPM) (Twa3)

Gene Name

MPHOSPH8 MPP8

UniProt

Q99549

Host

Mouse

Reactivity

Human

Immunogen

Fusion protein amino acids 50-120 (Chromo domain) of human MPP8 (accession number Q99549) produced recombinantly in E. Coli

Target

MPP8

Clonality

Monoclonal

Isotype

IgG2b

Clone

N119/44

Type

Primary Antibody

Applications

ICC

Field of Research

Epigenetics

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

100 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

ICC Quality Control

1

Conjugate

FL594 Ex: 594 nm, Em: 615 nm

RRID

AB_2939570

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