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Anti-Neuroligin-4* Antibody FL490 Conjugate

Our Anti-Neuroligin-4* mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N98/7. It detects mouse Neuroligin-4*, and is purified by Protein A chromatography. It is great for use in ICC.

Product Specifications

Background

Neuroligin4 is encoded by the gene NLGN4. Neuroligin4 is a transmembrane scaffolding protein and cell adhesion molecule. It is involved in cell-cell interactions in neurons and in other cell types. It is expressed in many tissues, including retina and brain, where it is located at the postysynaptic membrane and is involved in regulation of synapses, synapse formation and synaptic transmission. Diseases associated with this gene include forms of Autism and Asperger Syndrome.

Short Description

Our Anti-Neuroligin-4* mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N98/7. It detects mouse Neuroligin-4*, and is purified by protein a chromatography. It is great for use in ICC.

Synonyms

Neuroligin 4-like (Neuroligin-4) (NL-4)

Gene Name

Nlgn4l Nl4* Nlgn4 Nlgn4x

UniProt

ABS19580

Host

Mouse

Reactivity

Mouse

Immunogen

Fusion protein amino acids 782-945 (intracellular C-terminus) of mouse Neuroligin-4* (accession number ABS19580) produced recombinantly in E. Coli

Target

Neuroligin-4*

Clonality

Monoclonal

Isotype

IgG1

Clone

N98/7

Type

Primary Antibody

Applications

ICC

Field of Research

Cell Adhesion Molecules

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

125-130 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

Does not cross-react with other Neuroligins

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Mouse

WB Brain Quality Control

1

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

RRID

AB_2939512

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