What is the catalog number for Anti-GABA-A-R, Beta1 Antibody?

The catalog number for Anti-GABA-A-R, Beta1 Antibody is 75-137-020.

What sizes are available for Anti-GABA-A-R, Beta1 Antibody?

Anti-GABA-A-R, Beta1 Antibody is available in the following size(s): 20 µL.

Is Anti-GABA-A-R, Beta1 Antibody in stock?

Anti-GABA-A-R, Beta1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Anti-GABA-A-R, Beta1 Antibody

Our Anti-GABA (A) R, Beta1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N96/55. It detects human and mouse GABA (A) R, Beta1, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Product Specifications

Background

Gamma-aminobutyric acid receptor subunit beta-1 or -GABA AR-Beta1 is encoded by the gene GABRB1 GABAA receptors are members of the Cys-loop family of ligand-gated ion channels. GABA AR alpha 5 is a subunit of the pentameric GABA receptors where GABA is the major inhibitory neurotransmitter in the vertebrate brain and mediates neuronal inhibition by binding to the GABA receptor and opening an integral chloride channel. GABA AR-Beta1 is primarily expressed in brain at the cell junction, synapse, and the postsynaptic cell membrane. Diseases associated with GABRB1 include early infantile epileptic encephalopathy 43, neurotic disorder, schizophrenia and autism.

Short Description

Our Anti-GABA (A) R, Beta1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N96/55. It detects human, mouse, and rat GABA (A) R, Beta1, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, IP, ELISA.

Synonyms

Gamma-aminobutyric acid receptor subunit beta-1 (GABA (A) receptor subunit beta-1)

Gene Name

Gabrb1

UniProt

P50571

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 327-450 of mouse GABA-A-R-Beta1 (accession number P50571) produced recombinantly in E. Coli

Target

GABA (A) R, Beta1

Clonality

Monoclonal

Isotype

IgG1

Clone

N96/55

Type

Primary Antibody

Applications

WB, IHC, ICC, IP, ELISA

Field of Research

Neurotransmitter Receptors

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.64

Molecular Weight

55 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

IHC Dilution

1:200

WB Dilution

1:1000

Specificity

No cross-reactivity against GABA-A-R-Beta2 or -Beta3

ICC Dilution

1:200

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.