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Anti-FGF12/FHF1 Antibody

Our Anti-FGF12/FHF1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N94/17. It detects human, mouse, and rat FGF12/FHF1, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP.

Product Specifications

Background

Fibroblast growth factor 12, FHF1 or FGF12 is encoded by the gene FGF12. FHF1 is a member of the fibroblast growth factor homologous factors family (a subfamily of fibroblast growth factors.) . FHFs have a role in regulation of voltage fated sodium channels (Nav channels) and are thought to be involved in nervous system development. FGF12 has been found to be expressed in the brain, eye and testis. Diseases associated with FGF12 include Early Infantile Epileptic Encephalopathy, Ebstein anomaly and Autosomal Dominant Deafness.

Short Description

Our Anti-FGF12/FHF1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N94/17. It detects human, mouse, and rat FGF12/FHF1, and is purified by protein a chromatography. It is great for use in IHC, ICC, IP, ELISA.

Synonyms

Fibroblast growth factor 12 (FGF-12) (Fibroblast growth factor homologous factor 1) (FHF-1) (Myocyte-activating factor)

Gene Name

FGF12 FGF12B FHF1

UniProt

P61328

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 1-243 (full-length) of human FGF12a (accession number P61328) produced recombinantly in E. Coli

Target

FGF12/FHF1

Clonality

Monoclonal

Isotype

IgG1

Clone

N94/17

Type

Primary Antibody

Applications

IHC, ICC, IP, ELISA

Field of Research

Neurogenesis and Development

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.61

Molecular Weight

27 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

IHC Dilution

1:100

WB Dilution

1:200

Specificity

Cross-reacts with FGF12b/FHF1bDoes not cross-react with FGF11/FHF3, FGF13/FHF2 or FGF14/FHF4

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

ICC Quality Control

1

Conjugate

Unconjugated

RRID

AB_2278408

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