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Anti-Malin Antibody

Our Anti-Malin mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N85/18. It detects human, mouse, non-human primate, rat Malin, and is purified by Protein A chromatography. It is great for use in ICC, WB.

Product Specifications

Background

NHL Repeat Containing E3 Ubiquitin Protein Ligase 1 is encoded by the gene NHLRC1. NHLRC1 is an E3 ubiquitin-protein ligase which is involved in the clearance of toxic polyglucosan and protein aggregates via multiple pathways. NHLRC1 is expressed in the brain, spinal cord, heart, liver, skeletal muscle, and pancreas. Diseases associated with NHLRC1 include Myoclonic Epilepsy of Lafora and Epilepsy.

Short Description

Our Anti-Malin mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N85/18. It detects human, mouse, non-human primate, and rat Malin, and is purified by protein a chromatography. It is great for use in WB, ICC, ELISA.

Synonyms

E3 ubiquitin-protein ligase NHLRC1 (EC 2.3.2.27) (Malin) (NHL repeat-containing protein 1) (RING-type E3 ubiquitin transferase NHLRC1)

Gene Name

NHLRC1 EPM2B

UniProt

Q6VVB1

Host

Mouse

Reactivity

Human, Mouse, Non-Human Primate, and Rat

Immunogen

Fusion protein amino acids 1-395 (full-length) of human malin (accession number AAQ19671) produced recombinantly in E. Coli

Target

Malin

Clonality

Monoclonal

Isotype

IgG1

Clone

N85/18

Type

Primary Antibody

Applications

WB, ICC, ELISA

Field of Research

Rare Diseases

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.55

Molecular Weight

42 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

ICC Quality Control

1

Conjugate

Unconjugated

RRID

AB_2153100

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