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Anti-GIT2 Antibody FL490 Conjugate

Our Anti-GIT2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N83/48. It detects human, mouse, and rat GIT2, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Product Specifications

Background

G-protein coupled receptor kinase interacting ArfGAP 2 is encoded by the gene GIT2. GIT2 is a member of the GIT protein family. GIT2 has a be shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. GIT2 is expressed in 207 organs with the highest expression level in the right hemisphere of cerebellum. Diseases associated with GIT2 include Gastric Antral Vascular Ectasia and Systemic Scleroderma.

Short Description

Our Anti-GIT2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N83/48. It detects human, mouse, and rat GIT2, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Synonyms

ARF GTPase-activating protein GIT2 (ARF GAP GIT2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT-2) (CAT2) (G protein-coupled receptor kinase-interactor 2) (GRK-interacting protein 2)

Gene Name

GIT2 KIAA0148

UniProt

Q14161

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Fusion protein amino acids 450-759 (C-terminus) of human GIT2 (accession number Q14161) produced recombinantly in E. Coli

Target

GIT2

Clonality

Monoclonal

Isotype

IgG1

Clone

N83/48

Type

Primary Antibody

Applications

IHC, ICC

Field of Research

Scaffold Proteins

Concentration

0.5 mg/mL

Format

Purified by Protein A chromatography

Buffer

PBS with 0.09% azide

Molecular Weight

85 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity against GIT1

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Human

ICC Quality Control

1

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

RRID

AB_2939468

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