What is the catalog number for Anti-GABA-B-R2 Antibody?

The catalog number for Anti-GABA-B-R2 Antibody is 75-124.

What sizes are available for Anti-GABA-B-R2 Antibody?

Anti-GABA-B-R2 Antibody is available in the following size(s): 100 µL.

Is Anti-GABA-B-R2 Antibody in stock?

Anti-GABA-B-R2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Anti-GABA-B-R2 Antibody

Our Anti-GABA (B) R2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N81/2. It is KO validated, detects human and mouse GABA (B) R2, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Product Specifications

Background

Gamma-aminobutyric acid type B receptor subunit 2 or GABA BR2 is encoded by the gene GABBR2. GABA BR2 is a subunit of the G-protein coupled receptor for the neurotransmitter GABA (gamma-aminobutyric acid) . It will inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters and the activity of ion channels and adenylyl cyclase. GABA BR2 is highly expressed in brain, especially in cerebral cortex, thalamus, hippocampus at the cell junction, synapse, the postsynaptic cell membrane and cytoplasmic vesicle membrane. It is weakly expressed in heart, testis and skeletal muscle. Diseases associated with GABBR2 include Neurodevelopmental Disorder With Poor Language And Loss Of Hand Skills, Rett syndrome- and Early Infantile Epileptic Encephalopathy 59.

Short Description

Our Anti-GABA (B) R2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N81/2. It is KO validated, detects human and mouse GABA (B) R2, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, ELISA.

Synonyms

Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) (HG20)

Gene Name

GABBR2 GPR51 GPRC3B

UniProt

O75899

Host

Mouse

Reactivity

Human and Mouse

Immunogen

Fusion protein amino acids 861-912 of rat GABABR2 (accession number NP_113990) produced recombinantly in E. Coli

Target

GABA (B) R2

Clonality

Monoclonal

Isotype

IgG1

Clone

N81/2

Type

Primary Antibody

Applications

WB, IHC, ICC, ELISA

Field of Research

Neurotransmitter Receptors

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.51

Molecular Weight

105 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity against GABABR1

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Rat

WB Brain Quality Control

Conjugate

Unconjugated

RRID

AB_10672845

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