Anti-SynCAM1 Antibody FL490 Conjugate

SynCAM1 cell adhesion molecule, Immunoglobulin superfamily member 4 (IgSF4), or Nectin-like protein 2 (NECL-2) is encoded by the gene CADM1 and is a member of the Immunoglobulin-like Cell Adhesion Molecules family. SynCam1 is a cell adhesion molecule involved in many cell processes including the mediation of cell-cell adhesion and assembly, neuronal migration axon growth and differentiation. SynCAM1 is expressed in many tissue types including, brain, lung, kidney, heart, spleen and liver. Diseases associated with this gene include Retroperitoneal Fibrosis and Neuromyelitis Optica Spectrum Disorder.

Our Anti-SynCAM1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L45/30. It detects human, mouse, and rat SynCAM1, and is purified by protein a chromatography. It is great for use in ICC.

Cell adhesion molecule 1 (Immunoglobulin superfamily member 4) (IgSF4) (Nectin-like protein 2) (NECL-2) (Spermatogenic immunoglobulin superfamily) (SgIgSF) (Synaptic cell adhesion molecule) (SynCAM) (Tumor suppressor in lung cancer 1) (TSLC-1)

Fusion protein amino acids 257-388 of mouse SynCAM1 (accession number Q8R5M8), recognizes 1.4b isoform only (epitope narrowed to GLTQLPNSAEELDSEDLS) produced recombinantly in E. Coli

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.