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Anti-TrpC4 Antibody

Our Anti-TrpC4 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N77/15. It detects human, mouse, and rat TrpC4, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.

Product Specifications

Background

Short transient receptor potential channel 4 or TrpC4 is encoded by the gene TrpC4. TrpC4 belongs to the transient receptor family, a group of membrane bound ion channels that have a relatively non-selective permeability to cations, including sodium, calcium and magnesium. This protein is thought to have a role as a cell-cell contact-dependent endothelial calcium entry channel. Trpc4 is found in many tissues including CNS, placenta, heart, smooth muscle, testis, kidney and brain. Mutations in this gene areassociated with generalized epilepsy with photosensitivity.

Short Description

Our Anti-TrpC4 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N77/15. It detects human, mouse, and rat TrpC4, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, IP, ELISA.

Synonyms

Short transient receptor potential channel 4 (Trp4) (TrpC4) (Capacitative calcium entry channel 1) (CCE1)

Gene Name

Trpc4

UniProt

O35119

Host

Mouse

Reactivity

Human, Mouse, and Rat

Immunogen

Synthetic peptide amino acids 930-947 (FKSEKVVVEDTVPIIPKE) of rat TrpC4 (accession number O35119)

Target

TrpC4

Clonality

Monoclonal

Isotype

IgG2b

Clone

N77/15

Type

Primary Antibody

Applications

WB, IHC, ICC, IP, ELISA

Field of Research

Ion Channels and Modulators/Trp Channels

Concentration

1 mg/mL

Format

Purified by Protein A chromatography

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.46

Molecular Weight

110 kDa

Shipping Conditions

Shipped on ice packs

Storage Conditions

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Recommended Usage

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Physical Properties

Liquid

Immunogen Species

Rat

ICC Quality Control

1

Conjugate

Unconjugated

RRID

AB_2256454

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